We are in constant pursuit of breakthroughs that improve patients' lives. We innovate each day to make the world a healthier place. It was Charles Pfizer's original vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies deliver better results, are more innovative, draw and keep the best talent, and know how to harness the power of those people. Pfizer's purpose—Breakthroughs that improve patients' lives—fuels everything we do and demonstrates our passion for expanding our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has meaning and reflects the value we work to bring to patients and society. Our purpose makes certain that patients continue to be at the centre of all we do. We live our purpose by seeking the best science in the world, collaborating with others in the healthcare system to increase access to our medicines, using digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to campaign for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.